Gene-Trait Similarity Regression for Multimarker-Based Association Analysis
نویسندگان
چکیده
منابع مشابه
Analysis of gene-gene interactions using gene-trait similarity regression.
OBJECTIVE Gene-gene interactions (G×G) are important to study because of their extensiveness in biological systems and their potential in explaining missing heritability of complex traits. In this work, we propose a new similarity-based test to assess G×G at the gene level, which permits the study of epistasis at biologically functional units with amplified interaction signals. METHODS Under ...
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ژورنال
عنوان ژورنال: Biometrics
سال: 2009
ISSN: 0006-341X
DOI: 10.1111/j.1541-0420.2008.01176.x